Urea Transporter UT3 Functions as an Efficient Water Channel
نویسندگان
چکیده
منابع مشابه
At physiological expression levels the Kidd blood group/urea transporter protein is not a water channel.
The Kidd (JK) blood group locus encodes a urea transporter that is expressed on human red cells and on endothelial cells of the vasa recta in the kidney. Here, we report the identification in human erythroblasts of a novel cDNA, designated HUT11A, which encodes a protein identical to the previously reported erythroid HUT11 urea transporter, except for a Lys(44) --> Glu substitution and a Val-Gl...
متن کاملUrea Transporter Inhibitors as Novel Diuretics
Urea transporter (UT) proteins, including isoforms of UT-A in kidney tubule epithelia and UT-B in vasa recta endothelia and erythrocytes, play an important role in the urine concentration mechanism by mediated an intra renal urea recycling, suggesting that functional inhibition of these proteins could have therapeutic use as a novel class of diuretic. Recently several classes of UT inhibitors h...
متن کاملUpregulation of urea transporter UT-A2 and water channels AQP2 and AQP3 in mice lacking urea transporter UT-B.
The UT-B urea transporter is the major urea transporter in red blood cells and kidney descending vasa recta. Humans and mice that lack UT-B have a mild urine-concentrating defect. Whether deletion of UT-B altered the expression of other transporter proteins involved in urinary concentration was tested. Fluorescence-based real-time reverse transcription-PCR and Northern blot analysis showed upre...
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چکیده ندارد.
An efficient secure channel coding scheme based on polar codes
In this paper, we propose a new framework for joint encryption encoding scheme based on polar codes, namely efficient and secure joint secret key encryption channel coding scheme. The issue of using new coding structure, i.e. polar codes in Rao-Nam (RN) like schemes is addressed. Cryptanalysis methods show that the proposed scheme has an acceptable level of security with a relatively smaller ke...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1998
ISSN: 0021-9258
DOI: 10.1074/jbc.273.16.9369